(FB 1548268885 Timestamp)
via Brandon Hayes and Rosenborg Predmetsky
This is super interesting
“Cultureâgene coevolutionary theory posits that cultural values have evolved, are adaptive and influence the social and physical environments under which genetic selection operates. Here, we examined the association between cultural values of individualismâcollectivism and allelic frequency of the serotonin transporter functional polymorphism (5-HTTLPR) as well as the role this cultureâgene association may play in explaining global variability in prevalence of pathogens and affective disorders. We found evidence that collectivistic cultures were significantly more likely to comprise individuals carrying the short (S) allele of the 5-HTTLPR across 29 nations.
Results further show that historical pathogen prevalence predicts cultural variability in individualismâcollectivism owing to genetic selection of the S allele. Additionally, cultural values and frequency of S allele carriers negatively predict global prevalence of anxiety and mood disorder. Finally, mediation analyses further indicate that increased frequency of S allele carriers predicted decreased anxiety and mood disorder prevalence owing to increased collectivistic cultural values.
Taken together, our findings suggest cultureâgene coevolution between allelic frequency of 5-HTTLPR and cultural values of individualismâcollectivism and support the notion that cultural values buffer genetically susceptible populations from increased prevalence of affective disorders.
Implications of the current findings for understanding cultureâgene coevolution of human brain and behaviour as well as how this coevolutionary process may contribute to global variation in pathogen prevalence and epidemiology of affective disorders, such as anxiety and depression, are discussed.”